{"id":1983,"date":"2025-06-12T10:34:29","date_gmt":"2025-06-12T02:34:29","guid":{"rendered":"https:\/\/troxerutin.com\/?p=1983"},"modified":"2025-06-09T10:34:56","modified_gmt":"2025-06-09T02:34:56","slug":"anti-tumor-application-of-nobiletin-2","status":"publish","type":"post","link":"https:\/\/troxerutin.com\/?p=1983","title":{"rendered":"Anti-tumor Application of Nobiletin"},"content":{"rendered":"Nobiletin has a significant inhibitory effect on a variety of tumor cells, and its anti-tumor mechanism mainly includes the following aspects:<br \/><br \/>Inhibit tumor cell proliferation: Nobiletin can inhibit tumor cell proliferation by regulating cell cycle-related proteins.<br \/><br \/>Induce cell apoptosis: By activating multiple signaling pathways (such as PI3K\/Akt\/mTOR pathway, endoplasmic reticulum stress, etc.), Nobiletin can induce tumor cell apoptosis.<br \/><br \/>Inhibit tumor cell migration and invasion: Nobiletin can reduce the migration and invasion ability of tumor cells by inhibiting related signaling pathways (such as ERK, JNK pathway) and the expression of matrix metalloproteinases (MMPs).<br \/><br \/>Combined with chemotherapy drugs to enhance the anti-tumor effect: When Nobiletin is used in combination with chemotherapy drugs, it can enhance the anti-tumor effect of chemotherapy drugs.","protected":false},"excerpt":{"rendered":"<p>Nobiletin has a significant inhibitory effect on a vari [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1983","post","type-post","status-publish","format-standard","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/posts\/1983","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/troxerutin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1983"}],"version-history":[{"count":1,"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/posts\/1983\/revisions"}],"predecessor-version":[{"id":1984,"href":"https:\/\/troxerutin.com\/index.php?rest_route=\/wp\/v2\/posts\/1983\/revisions\/1984"}],"wp:attachment":[{"href":"https:\/\/troxerutin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1983"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/troxerutin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1983"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/troxerutin.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1983"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}